HPV vaccination is not recommended for everyone older than age 26 years. However, some adults age 27 through 45 years who are not already vaccinated may decide to get the HPV vaccine after speaking with their doctor about their risk for new HPV infections and the possible benefits of vaccination. HPV vaccination in this age range provides less benefit, as more people have already been exposed to HPV.
If vaccination is started before age 15, a two-dose schedule is recommended, with the doses given 6 to 12 months apart. For people who start the series after their 15th birthday, the vaccine is given in a series of three shots.
HPV vaccination prevents new HPV infections, but does not treat existing infections or diseases. This is why the HPV vaccine works best when given before any exposure to HPV. You should get screened for cervical cancer regularly, even if you received an HPV vaccine.
A woman’s vagina -- their birth canal -- is a channel that goes from the opening of their uterus to the outside of their body. Many kinds of cancer can spread to the vagina from somewhere else, but cancer that starts here is rare. There are about 6,000 new cases in the U.S. each year.
Squamous cell carcinoma. This is by far the more common. It happens when cancer forms in the flat, thin cells that line your vagina. This type spreads slowly and tends to stay close to where it starts, but it can move into other places like your liver, lungs, or bones. Older women are most likely to get this form. Nearly half of all new cases are in women ages 60 and up.
Adenocarcinoma. This type starts in glandular cells in the lining of your vagina, which make mucus and other fluids. It’s more likely to spread to other areas, including your lungs and the lymph nodes (small organs that filter out harmful things in your body) in your groin.
Clear cell carcinoma. This is an even rarer form of adenocarcinoma. It often affects women whose mothers took a hormone called diethylstilbestrol (DES) in the early months of pregnancy. Between 1938 and 1971, doctors often prescribed this medication to prevent miscarriage and other problems.
Even more rarely, vaginal cancer can form in connective tissue or muscle cells (sarcoma) or in cells that make pigments (melanoma).
Some cases of vaginal cancer don’t have a clear cause. But most are linked to infection with the human papillomavirus, or HPV. This is the most common sexually transmitted disease (STD). An HPV infection most often goes away on its own, but if it lingers, it can lead to cervical and vaginal cancer.
Vaginal Cancer After PeriodYou also might be more likely to get vaginal cancer if you: Are 60 or older Were exposed to DES Drink alcohol Have cervical cancer or precancerous lesions Have HIV Smoke Have unusual cells in your vagina called vaginal intraepithelial neoplasia Vaginal Cancer Symptoms Vaginal cancer often doesn’t cause symptoms. Your doctor might find it during a routine exam or Pap test. If you have symptoms, they can include:
Unusual bleeding from your vagina Watery or bad-smelling discharge from your vagina Pain in your pelvis Pain when having sex Pain when peeing Peeing more than usual Constipation A lump in your vagina If you notice any of these things, it doesn’t mean you have vaginal cancer. You could just have an infection. But it’s important to get it checked out.
If a pelvic exam or a Pap test shows signs of a problem, your doctor may want to take a closer look by doing a colposcopy. They’ll use a lighted magnifying tool called a colposcope to check your vagina and cervix for anything unusual.
They might also take out a bit of tissue so a specialist can look at it under a microscope. This is called a biopsy.
After your doctor diagnoses vaginal cancer, they’ll do imaging tests and other exams to find out whether it’s spread to other parts of your body. This helps them decide the stage the cancer and how to treat it. The stages are:
You and your doctor will decide on treatment based on many things, including how close the cancer is to other organs, its stage, whether you’ve had radiation treatment in your pelvic area, and whether you’ve had a hysterectomy to remove your uterus.
Your doctor will probably recommend one or more of these treatments: Surgery. This is the most common treatment. Your doctor may use a laser to cut out tissue or growths. In some cases, they might remove all or part of your vagina. You may need a hysterectomy to remove your cervix or other organs. Many women can have a normal sex life after surgery. But sex can raise your chances of infection, and it can cause bleeding or strain the surgical site. Your doctor will tell you what’s safe to do and when it's safe.
Radiation therapy. This treatment uses high-powered X-rays or other forms of radiation to kill cancer. Your doctor might use a machine that sends X-rays into your body, or they could insert a radioactive substance inside your body, on or near the cancer. Radiation treatments in your pelvic area can damage your ovaries. That can cause them to stop making estrogen, leading to menopause symptoms like hot flashes and vaginal dryness. If you’ve been through menopause, you probably won’t have these problems. This type of therapy also can irritate healthy tissue. Your vagina might get swollen and tender. Sex may be painful. Chemotherapy (“chemo”). This uses medication to kill or stop the growth of cancer cells. You might take the medication by mouth or get it injected into a vein (intravenous or IV). In some cases, your doctor might give you a chemo in lotion or cream form.
You may lose your sex drive or have side effects like nausea, hair loss, and changes in body weight. These will improve or go away after treatment. Vaginal Cancer Prognosis Your recovery depends on many things. The most crucial is the stage at which your doctor found your cancer. At the earliest stages, doctors can often cure vaginal cancer. Five-year survival rates are around 67% for women at stages I and II. This means that 5 years after they were diagnosed or treated, 67% of women are still alive. It's about 47% for all stages combined.
Your age, your overall health, whether your cancer is new or has come back, and whether it caused symptoms also play a role in recovery. Vaginal Cancer Prevention The best way to protect yourself is to avoid getting HPV. The FDA has approved the Gardasil 9 vaccine to prevent HPV-related diseases, including the seven most common types of HPV that cause cancer. The vaccine is for people ages 9 to 45. Younger patients need fewer shots for full protection. Certain lifestyle changes can also help reduce your risk of vaginal cancer:
Wait to have sex until your late teen years or beyond. Don’t have sex with more than one partner. Don’t have sex with someone who has more than one partner. Use condoms during sex. Get regular Pap exams. If you smoke, stop. If you don’t smoke, don’t start. Vaginal cancer is a rare cancer that usually forms in your vaginal lining. You’re at a higher risk of developing it if you’re over 60 or have HPV. Vaginal cancer doesn’t always cause symptoms, which is why it’s a good idea to get regular pelvic exams and Pap smears to detect cancer early. APPOINTMENTS & ACCESS CONTACT US Symptoms and Causes Diagnosis and Tests Management and Treatment Prevention Outlook / Prognosis Frequently Asked Questions OVERVIEW
Pelvic exenteration: This surgery removes multiple organs from your pelvis, including the bottom part of your colon (rectum), bladder, uterus, cervix, vagina, ovaries and nearby lymph nodes. Your provider will make an opening in your abdomen that will allow you to pee and poop (called a stoma or ostomy bag). This type of surgery may be an option if you have recurring cancer.
Radiation uses targeted energy beams, like X-rays, to destroy cancer cells or keep them from dividing.
External radiation therapy: A machine outside your body directs beams of high-energy radiation at your tumor.
Internal radiation therapy: Sealed wires or catheters containing radioactive material are placed inside your vagina, either into or near the tumor.
Chemotherapy uses drugs to kill cancer cells. Chemotherapy alone isn’t an effective treatment for vaginal cancer, but it may be used alongside radiation to enhance its effectiveness. Sometimes, chemotherapy is used to treat tumors that disappear with treatment and later return.
Your provider may recommend you take part in a clinical trial to try new cancer treatments in development. The American Cancer Society and the National Cancer Institute are good resources for locating current clinical trials involving vaginal cancer treatments.
How can I reduce my risk of getting vaginal cancer?
You can’t prevent vaginal cancer, but you can reduce your risk.
Get regular pelvic exams and Pap tests. Talk with your provider about how regularly you should be receiving routine checks from your gynecologist.
Vaginal Cancer PreventionGet the HPV vaccine. Talk to your provider about getting vaccinated against HPV. Currently, there are three FDA-approved vaccines available, Gardasil, Gardasil 9 and Cervarix.
Don’t smoke. Smoking increases your risk of all cancers, including vaginal cancer.
Your prognosis for vaginal cancer depends on the stage at which it’s diagnosed. Early-stage vaginal cancers can often be successfully treated, and you can go on to live a full life. Later-stage cancers are harder to treat and may require ongoing chemotherapy and other treatment options. For this reason, it’s important to get regular gynecological exams, even when you feel healthy. Seek medical advice at the first sign of symptoms.
Yes. But it’s rare for cancer to begin in your vagina, as with vaginal cancer. More often, cancers that begin in other parts of your body spread to your vagina. Cancers that spread to your vagina most commonly begin in your cervix (cervical cancer) or the lining of your uterus (uterine cancer/endometrial cancer).
Vaginal bleeding is a common symptom of multiple cancers, including vaginal cancer, cervical cancer, uterine cancer and ovarian cancer. But abnormal bleeding is a common sign of multiple conditions, not just cancer. Don’t assume you have cancer if you have unusual bleeding. Still, see your healthcare provider to get checked.
The most common symptom of vaginal cancer is painless vaginal bleeding, which means you may not feel vaginal cancer at all. Less commonly, you may experience pain in your pelvis, painful urination or discomfort related to constipation.
If you receive a vaginal cancer diagnosis, it’s important to have an honest discussion with your provider about the type of cancer, if it’s spread, and what your treatment options are. Your prognosis will depend on multiple factors. Your provider is your best resource for explaining what this diagnosis means for you.
In the meantime, establishing a support network that includes family members, friends, current cancer patients and cancer survivors is an essential part of your care plan, too. The American Cancer Society can connect you with cancer support groups. Speak to a counselor to process your diagnosis. Getting your emotional needs met is as important as the clinical care you receive.
Vaginal cancer is a rare cancer that occurs in your vagina — the muscular tube that connects your uterus with your outer genitals. Vaginal cancer most commonly occurs in the cells that line the surface of your vagina, which is sometimes called the birth canal.
While several types of cancer can spread to your vagina from other places in your body, cancer that begins in your vagina (primary vaginal cancer) is rare.
A diagnosis of early-stage vaginal cancer has the best chance for a cure. Vaginal cancer that spreads beyond the vagina is much more difficult to treat.